![]() The J-1500 can be beneficial for those who are involved in research, because of its extensive expandability options. The J-1100 compact instrument is recommended primarily for those who wish to use it to characterize bio and organic molecules as a routine task. The J-1100 and J-1500 instruments are considered as the successors of the JASCO J-815 CD spectrometers. With these instruments the kinetics of enzyme and organic reactions, the DNA/RNA interactions, the structure and conformation of proteins can also be examined. It can be used for monitoring the stereoselective processes and for studying the conformational changes caused by temperature, pH and chemical reactions. The CD spectrometers are the basic instruments for measuring the absolute configuration and conformation of the organic compounds. This instrument, also known as dichrograph, spectropolarimeter, circular dichroism spectrometer (CD) or electronic circular dichroism spectrometer (ECD) is capable of both the qualitative and quantitative testing of compounds in whose molecules chromophore groups can be found near the chiralty centers. The Japanese company JASCO has been collecting its experience in the field of CD spectrometers, the most important chiroptical instruments used for the measurement of circular dichroism phenomenon since 1961. Surface plasmon resonance (SPR) instruments.Vision Microette – diffusion cell systems.Hanson Sample Preparation Extractor (XTRX500).DissoClean Mark1 dissolution vessel washer.Hanson On-line UV-Vis dissolution systems.JASCO LC-4000 HPLC / RHPLC / UHPLC systems.NRS-5000/7000 dispersive Raman spectrometers. ![]() Lisa Warner at 20 or by email at for more information. J-810 Series Hardware Function Manual (PDF)įor rate information please see BRC Recharge Rates found here.Circular Dichroism_Greenfield 2004 (PDF).UCI Department of Chemistry Introduction to circular dichroism (PDF).Qualified users will be able to book instrument time and use the instrument independently. First-time users please contact the BRC for information on training and access requirements. The purpose of this instrument is to support research at Boise State University and surrounding research facilities. Thermodynamic parameters from temperature dependencies of CD signals.Kinetics of folding and unfolding of macromolecules.Determination of the thermodynamically dependent folding and unfolding of proteins and nucleic acids.Structural comparison between wild-type and mutant proteins.Determination of the conformational changes of protein and nucleic due to molecular interactions.Estimation of protein and nucleic acid conformation.It is equipped with a computer-controlled Peltier device (3-90 ☌) and a two-syringe titrator to assess thermal/chemical stabilities of proteins/ polypeptides or to monitor ligand binding and is controlled by Jasco’s Spectra Manager software. It is designed to allow secondary structure determination by circular dichroism specifically measuring the left-and right-handed circularly polarized light of optically active molecules. The Jasco J-810 Spectropolarimeter (163-900 nm) is a hybrid instrument consisting of a variable wavelength polarimeter and absorption spectrophotometer.
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